Looking for an audio interface with MIDI ports that fits your studio, setup, and budget? The right choice can simplify recording, improve sound quality, and keep your instruments connected without extra adapters.
In this roundup, we focus on practical picks for musicians, producers, streamers, and home-recording users who want solid audio performance plus dependable MIDI connectivity.
Best 10 Audio Interface with Midi Ports Picks for 2026
Budget 4x4 Recording Hub
Behringer U-PHORIA UMC404HD Audiophile 4x4
- 4x4 USB audio with 1x MIDI I/O
- 24-bit/192 kHz recording quality
- Four MIDAS-designed mic preamps
Best For: Home studios needing multi-input recording and MIDI support
Simple USB-C Starter Interface
Focusrite Scarlett 2i2 4th Gen USB-C
- USB-C 2-channel interface with 120dB dynamic range
- Auto Gain, Clip Safe, and Air mode
- Includes Pro Tools Intro+ and other software
Best For: Beginners and solo artists who do not need MIDI
Direct MIDI Cable Interface
- 1 in/1 out MIDI connection
- Plug-and-play with built-in driver
- Supports Windows, macOS, and iPad setups
Best For: Players needing a compact MIDI link for keyboards and synths
Expandable Studio Hub
Focusrite Scarlett 4i4 4th Gen USB-C
- MIDI I/O with 4-in/4-out routing
- 2 mic pres, 2 Hi-Z inputs, 4 line ins/outs
- Auto Gain, Clip Safe, and Air mode
Best For: Producers who need MIDI plus extra line routing
Compact MIDI-Friendly Recording
Mackie Onyx Producer 2X2 USB Audio Interface with MIDI
- Includes MIDI I/O for keyboards and hardware gear
- Two Onyx mic preamps with 48V phantom power
- Bus-powered USB 2.0 with zero-latency monitoring
Best For: Small studios and mobile musicians
Clean USB-C Monitoring Pick
- 24-bit/192kHz 2-in/2-out recording
- Hardware monitoring for low-latency tracking
- USB-C interface for Mac, Windows, and iOS
Best For: Windows, macOS, and iOS users
Simple Songwriter Interface
Focusrite Scarlett Solo 4th Gen USB-C Audio Interface
- 120dB dynamic range with updated converters
- Air mode adds presence to vocals and guitars
- Includes Pro Tools Intro+, Ableton Live Lite, and Cubase LE
Best For: Songwriters and solo creators
Portable 2-Channel MIDI Recording
PreSonus AudioBox 96 25th Anniversary USB Audio Interface
- Includes MIDI I/O with 2 mic preamps and 2 instrument inputs
- Bus-powered USB 2.0 design for portable recording
- Up to 24-bit/96 kHz with bundled DAW software
Best For: Singers, guitarists, and beginners needing a compact interface with MIDI
High-Resolution USB-C Compact Interface
ESI Amber i1 USB Audio Interface
- 24-bit/192 kHz conversion with low-latency performance
- USB-C powered with DirectWIRE loopback routing
- Combo input and separate line inputs for flexible recording
Best For: Solo creators and musicians who want high-resolution audio in a compact USB-C unit
Streamer-Friendly Compact Recording Interface
MAONO PS22 Lite USB Audio Interface
- 24-bit/192 kHz audio with 106 dB dynamic range
- 48V phantom power and 56 dB preamp gain for microphones
- ProStudio Routing Software supports loopback and virtual channels
Best For: Beginners, streamers, podcasters, and guitarists who want a simple compact interface
Budget 4×4 Recording Hub – Behringer U-PHORIA UMC404HD Audiophile 4×4
If you want an audio interface with midi ports that also gives you room to grow, the Behringer U-PHORIA UMC404HD is built for small studios that need multiple inputs without a big price jump. It combines 4×4 USB audio, 24-bit/192 kHz conversion, and MIDI I/O in a metal chassis designed for regular use.
Best For: Home recordists who need four inputs, MIDI connectivity, and a durable interface for band-style tracking.
Pros:
- 4×4 USB audio interface with 1x MIDI I/O for recording instruments and MIDI gear
- 24-bit/192 kHz resolution for high-quality recording and playback
- Four MIDAS-designed mic preamps with +48V phantom power
- Impact-resistant metal chassis for a more rugged desktop setup
Cons:
- USB 2.0 connection is less modern than USB-C options
- Larger than simple 2-input interfaces
This is a practical pick if your setup needs more than basic stereo recording and you want MIDI support built in. The extra inputs and outputs make it especially useful for tracking multiple sources at once.
Simple USB-C Starter Interface – Focusrite Scarlett 2i2 4th Gen USB-C
The Focusrite Scarlett 2i2 4th Gen is a straightforward audio interface with midi ports? No—this model focuses on clean two-channel recording rather than MIDI, which makes it a strong choice if your priority is vocals, guitar, and quick setup. Its USB-C connection, 120dB dynamic range, and included software make it easy to start recording right away.
Best For: Singer-songwriters and beginners who want a simple, high-quality 2-input interface without MIDI.
Pros:
- 4th Gen mic pres with studio-style 120dB dynamic range
- Auto Gain and Clip Safe help set levels and avoid distortion
- Air mode adds presence and harmonic drive to vocals and guitars
- Includes Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion
Cons:
- No MIDI I/O for keyboards or external MIDI gear
- Only 2 channels, so it’s less flexible for larger setups
For straightforward recording, this interface is polished and easy to live with. If you need MIDI ports, you’ll want a different model, but as a compact 2-channel interface it covers the essentials very well.
Direct MIDI Cable Interface – LEKATO MIDI to USB C Cable
If your goal is a compact audio interface with midi ports for keyboards and synths, the LEKATO MIDI to USB-C cable is a simple plug-and-play solution for standard MIDI connections. It offers 1 in/1 out MIDI handling, status indicators, and low-latency transmission for editing and recording sessions.
Best For: Keyboard players and synth owners who need a lightweight MIDI-to-USB-C connection for a computer or iPad.
Pros:
- 1 in + 1 out MIDI interface with indicators for easier troubleshooting
- Supports up to 16 input and output channels
- Ultra-low latency transmission with built-in driver and plug-and-play setup
- Works with Windows, macOS, and iPad-compatible MIDI setups
Cons:
- Not a full audio interface for microphones or instruments
- Compatibility may vary with some older or proprietary MIDI devices
This is best viewed as a dedicated MIDI connection rather than a studio audio hub. If you only need to move MIDI data reliably between hardware and software, it keeps the setup small and direct.
Expandable Studio Hub – Focusrite Scarlett 4i4 4th Gen USB-C
The Focusrite Scarlett 4i4 4th Gen is a strong pick if you need an audio interface with midi ports and more routing flexibility than a basic 2-channel model. With 2 mic preamps, 2 Hi-Z inputs, 4 line inputs, 4 line outputs, and MIDI I/O, it’s built for home studios that connect multiple pieces of gear.
Best For: Producers and multi-instrument setups that need MIDI I/O plus extra line inputs and outputs.
Pros:
- Includes MIDI I/O alongside 4-in/4-out routing
- 2 Scarlett mic preamps and 2 Hi-Z inputs for vocals and instruments
- 4 line inputs and 4 line outputs for more flexible studio setups
- Auto Gain, Clip Safe, and Air mode help streamline recording
Cons:
- More complex than a simple two-input interface
- May be more interface than solo vocal-only users need
If your setup includes synths, drum machines, and external MIDI gear, this model gives you more connection options without jumping to a large rack interface. It balances compact size with practical studio expansion.
Compact MIDI-Friendly Recording – Mackie Onyx Producer 2X2 USB Audio Interface with MIDI
Mackie Audio Interface, Onyx Producer 2X2 USB Audio Interface with MIDI (Onyx Producer 2-2)
Check Price On AmazonIf you want an audio interface with midi ports that still keeps the setup simple, the Mackie Onyx Producer 2X2 is built for straightforward 2-in/2-out recording. It offers 24-bit/192kHz capture, two Onyx mic preamps, and bus-powered USB 2.0 operation, so it can fit easily into a mobile or desktop studio.
Best For: Small studios and mobile musicians who need MIDI I/O, clean mic pres, and easy plug-and-play recording.
Pros:
- Includes MIDI I/O, making it a strong fit for keyboard rigs and hardware sequencing.
- Two boutique-quality Onyx mic preamps with 48V phantom power support condenser mics.
- Zero-latency direct monitoring with dedicated monitor outputs and a powerful headphone output.
- Bus-powered USB 2.0 design helps keep the setup portable and free of an extra power adapter.
Cons:
- Only 2-in/2-out, so it is not ideal for larger multi-source recording sessions.
- Best suited to basic recording workflows rather than expanded studio expansion.
The Onyx Producer 2X2 stands out if MIDI connectivity is a must and you want a compact interface with solid recording features. Its mix of portability, direct monitoring, and included software makes it a practical all-around starter or travel unit.
Clean USB-C Monitoring Pick – MOTU M2 USB-C Audio Interface
The MOTU M2 is a streamlined USB-C interface for users who want a dependable 2-in/2-out recording setup with hardware monitoring and 24-bit/192kHz support. It is a practical choice if you are comparing an audio interface with midi ports, but your actual priority is clean audio conversion and a simple two-channel workflow.
Best For: Windows, macOS, and iOS users who want a compact interface with strong monitoring and high-resolution recording.
Pros:
- 24-bit/192kHz recording with 2-in/2-out operation for basic home studio work.
- Hardware monitoring helps reduce latency during tracking.
- USB-C connectivity keeps the connection modern and convenient.
- Compatible with macOS, Windows, and iOS according to the supplied details.
Cons:
- No MIDI I/O is listed in the supplied notes.
- Only two channels, so it is not built for larger recording setups.
The M2 is best viewed as a no-fuss recording interface with strong everyday usability rather than a feature-heavy studio hub. If you do not need MIDI ports, it offers a focused and tidy workflow.
Simple Songwriter Interface – Focusrite Scarlett Solo 4th Gen USB-C Audio Interface
The Focusrite Scarlett Solo 4th Gen is a compact USB-C interface aimed at solo recording, with one XLR mic preamp and one Hi-Z instrument input. If you are shopping for an audio interface with midi ports, this one is not the fit, but it is a strong entry-level option for vocals and guitar with high-resolution 24-bit/192kHz recording.
Best For: Songwriters and solo creators recording vocals and guitar on Mac, Windows, or iPad.
Pros:
- 120dB dynamic range and updated converters for studio-quality sound.
- Improved Air mode adds presence and harmonic drive to vocals and guitars.
- Includes recording software and plugins such as Pro Tools Intro+, Ableton Live Lite, and Cubase LE.
- PC, Mac, and iPad compatible for flexible home or portable recording.
Cons:
- No MIDI ports are listed in the supplied product details.
- Only one mic preamp and one instrument input, so it is limited to solo recording.
This is a good pick for straightforward songwriter setups where sound quality and included software matter more than expandability. If you need MIDI connectivity or multi-input recording, you will want to look at a different interface.
Portable 2-Channel MIDI Recording – PreSonus AudioBox 96 25th Anniversary USB Audio Interface
If you want an audio interface with midi ports that stays simple and affordable, the PreSonus AudioBox 96 is a practical place to start. It gives you two Class-A mic preamps, two instrument inputs, and MIDI I/O in a bus-powered USB 2.0 design that suits compact home studios and mobile recording.
Best For: Singers, guitarists, and beginners who need a lightweight 2-channel interface with MIDI connectivity and bundled software.
Pros:
- Includes MIDI I/O alongside 2 mic preamps and 2 instrument inputs.
- Bus-powered USB 2.0 design keeps the setup portable and simple.
- Up to 24-bit/96 kHz recording with balanced TRS outputs and headphone monitoring.
- Comes with a large software bundle, including Studio One Artist and Ableton Live Lite.
Cons:
- Only 2 channels, so it is not built for larger tracking sessions.
- Uses USB 2.0 rather than newer USB-C connectivity.
- Global phantom power may be less flexible than per-channel control.
Overall, this is a straightforward audio interface with midi ports for users who value portability, included software, and easy monitoring over advanced routing. It covers the essentials well for solo recording and small setups.
High-Resolution USB-C Compact Interface – ESI Amber i1 USB Audio Interface
The ESI Amber i1 is a compact choice if you are shopping for an audio interface with midi ports-style flexibility in a small recording setup, though its supplied specs focus on audio inputs rather than dedicated MIDI hardware. What it does offer is a 2-in/2-out USB-C interface with studio-grade 24-bit/192 kHz conversion, DirectWIRE loopback, and simple controls for guitar, vocals, and streaming.
Best For: Solo creators, podcasters, and musicians who want a high-resolution USB-C interface with easy routing and strong input quality.
Pros:
- 24-bit/192 kHz converters for detailed recording and playback.
- USB-C power and simple setup make it easy to use on modern rigs.
- Combo XLR + 1/4-inch TRS input plus separate line inputs for flexible sources.
- DirectWIRE loopback and included software are useful for streaming and production.
Cons:
- Supplied notes do not list dedicated MIDI ports.
- Only 2 channels, so it is best for smaller recording tasks.
- Input options are focused on simple solo recording rather than multi-source tracking.
In practice, the Amber i1 is strongest as a clean, high-resolution compact interface for content creation and music work. If MIDI is a must-have, double-check your exact setup needs before buying.
Streamer-Friendly Compact Recording Interface – MAONO PS22 Lite USB Audio Interface
The MAONO PS22 Lite is a compact USB audio interface built for recording, streaming, and simple instrument setups. If you are comparing an audio interface with midi ports, note that the supplied details emphasize microphone, guitar, and routing features rather than dedicated MIDI connectivity, but it still offers a versatile all-in-one starter option.
Best For: Beginners, streamers, podcasters, and guitarists who want an easy-to-use interface with strong monitoring and routing tools.
Pros:
- 24-bit/192 kHz recording with a 106 dB dynamic range.
- Includes 48V phantom power and up to 56 dB of preamp gain for mics.
- Dedicated instrument input with impedance adjustment for guitar use.
- ProStudio Routing Software adds virtual channels and loopback for streaming.
Cons:
- Supplied notes do not mention dedicated MIDI ports.
- Only one compact unit of hardware, so it is aimed at simple setups.
- Best suited to solo work rather than larger multi-input sessions.
This interface makes sense if you want an easy plug-and-play path into recording or live streaming. It is especially appealing for users who care more about quick setup, direct monitoring, and routing than expanded hardware connections.
How We Picked the Best Audio Interface with Midi Ports
We focused on interfaces that balance sound quality, MIDI support, driver stability, input/output flexibility, and value. Because buyers have different needs, we included compact 2-in/2-out models for simple setups, as well as larger options for multi-source recording and MIDI-heavy workflows.
We also considered real-world usability: front-panel monitoring, gain control, USB-C compatibility, phantom power, instrument inputs, and bundle-friendly features that matter when you are building a practical studio.
Quick Comparison
For solo recording and portable setups, smaller units tend to be the easiest to live with. If you need to record vocals and an instrument at the same time, a 2×2 or 4×4 layout is more comfortable. For synth players and keyboard rigs, an Audio Interface with Midi Ports is especially useful because it reduces cable clutter and keeps timing and routing straightforward.
Key Buying Factors for an Audio Interface with Midi Ports
I/O Count and Workflow
Match the number of inputs and outputs to your real use case. Solo creators may only need one mic and one instrument input, while small bands, podcasters, and producers often benefit from extra line inputs and monitor outputs.
MIDI Connectivity
Check whether the interface includes standard 5-pin MIDI In/Out ports or whether you need a separate USB MIDI cable solution. Standard DIN ports are best if you regularly connect keyboards, drum machines, and synths.
Audio Quality and Monitoring
Look for clean mic preamps, 24-bit recording, and low-latency monitoring. These features matter more than flashy extras when you want dependable tracking and playback.
Platform and Power Compatibility
Make sure the interface works with your computer, recording software, and bus-power setup. USB-C is common now, but compatibility with Windows, macOS, and mobile workflows still varies by model.
Who Should Buy Which Audio Interface with Midi Ports?
If you want the simplest studio setup, a compact interface with one or two inputs is usually enough. If you record multiple sources, choose a model with more inputs and dedicated MIDI ports. Producers with keyboards or external sound modules should prioritize the best routing and stable MIDI handling over raw channel count alone.
If your work is mainly streaming, voice-over, or guitar-and-vocal recording, a straightforward interface with clean gain staging and easy monitoring may be the smartest buy. For broader studio expansion, a more feature-rich Audio Interface with Midi Ports can save you from upgrading again too soon.








